Description
Form: Ready to use vial | Purity: ≥99% | Storage: Refrigerate
What It Is
5-Amino-1MQ is a small molecule NNMT (Nicotinamide N-methyltransferase) inhibitor. NNMT is an enzyme that becomes overactive in fat tissue during obesity and aging, consuming NAD+ and promoting fat storage. Blocking NNMT restores NAD+ availability and shifts metabolism toward fat burning.
What It Does
5-Amino-1MQ reduces body fat, improves insulin sensitivity, increases NAD+ levels, activates SIRT1 (a longevity protein), and improves mitochondrial function. In animal studies it produced significant fat loss without changes to diet or exercise. It is particularly effective for visceral fat and metabolic dysfunction.
How It Works
By inhibiting NNMT, 5-Amino-1MQ prevents the enzyme from consuming NAD+. This raises intracellular NAD+ levels, which activates sirtuins and AMPK, shifting cellular metabolism toward fat oxidation and away from fat storage. It also reduces the size of fat cells and decreases fat cell proliferation.
Who Benefits Most
People with stubborn body fat, especially visceral fat. People with metabolic syndrome or insulin resistance. Anyone who wants to raise NAD+ levels through a different mechanism than direct supplementation. People interested in longevity and metabolic optimization.
Protocol and Dosing
Typical dose: 50 to 100 mg orally once daily. Can also be used as a sublingual or injectable compound. Cycle length: 4 to 12 weeks. Often stacked with NAD+ for synergistic effects.
| Route | Typical Dose | Frequency |
|---|---|---|
| Oral | 50 to 100 mg | Once daily |
Cautions
Limited long term human safety data. Use under practitioner supervision. Not recommended during pregnancy. Monitor liver function with extended use.
Pairs Well With
NAD+ for synergistic NAD+ restoration through complementary mechanisms. MOTS-C for comprehensive mitochondrial and metabolic optimization. Semaglutide or Tirzepatide for aggressive fat loss protocols.
Quality and Sourcing
Sourced through United Medical Services (UMS), a compounding facility built to the same standards as a licensed 503A pharmacy. Every batch is tested for purity, sterility, potency, and identity. Certificates of Analysis are available on request.
- HPLC purity testing
- LC-MS identity confirmation
- Sterility and endotoxin testing
- Heavy metals screening
- Purity: greater than or equal to 99%
For research and investigational use by qualified healthcare practitioners only. Not for human consumption. Not for resale. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Certificate of Analysis available on request. Questions? Call or text 507-382-2881.
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