KPV

$100.00

A tripeptide derived from alpha-MSH that inhibits NF-kB directly inside cells. Reduces gut inflammation, heals leaky gut, and improves IBD symptoms. One of the most targeted anti-inflammatory peptides available. COA available on request. Questions? Call 507-382-2881.

SKU: CVL-VIAL-74 Category:

Description

Form: Ready to use vial | Purity: ≥99% | Storage: Refrigerate

What It Is

KPV is a tripeptide (Lysine-Proline-Valine) derived from the C-terminal end of alpha-MSH. It retains the anti inflammatory properties of alpha-MSH without the melanocortin receptor activation that produces tanning and sexual effects. It is one of the most targeted anti inflammatory peptides available.

What It Does

KPV reduces systemic and local inflammation, heals the gut lining, reduces intestinal permeability (leaky gut), improves symptoms of inflammatory bowel disease, reduces skin inflammation, and has antimicrobial properties. It is particularly effective for gut-based inflammation and autoimmune conditions with a gut component.

How It Works

KPV enters cells and travels directly to the nucleus where it inhibits NF-kB, the master regulator of inflammatory gene expression. This intracellular mechanism is different from most anti inflammatory compounds, which work extracellularly. It also inhibits inflammatory cytokines including IL-1, IL-6, and TNF-alpha.

Who Benefits Most

People with IBD, Crohn’s disease, ulcerative colitis, or leaky gut. People with autoimmune conditions that have a gut component. Anyone with chronic systemic inflammation. People with skin conditions like psoriasis or eczema. Anyone looking to reduce inflammatory burden as part of a functional medicine protocol.

Protocol and Dosing

Oral or sublingual: 500 mcg to 1 mg daily for gut-specific effects. Injectable: 100 to 500 mcg subcutaneously once daily for systemic effects. Cycle length: 4 to 12 weeks.

Route Typical Dose Best For
Oral/sublingual 500 mcg to 1 mg Gut inflammation
Subcutaneous injection 100 to 500 mcg Systemic inflammation

Cautions

Excellent safety profile. Well tolerated at standard doses. No significant adverse effects reported in research. Not recommended during pregnancy.

Pairs Well With

BPC-157 for comprehensive gut healing and repair. TA-1 for immune modulation alongside anti inflammatory support. Glutathione for antioxidant support alongside inflammation reduction.

Quality and Sourcing

Sourced through United Medical Services (UMS), a compounding facility built to the same standards as a licensed 503A pharmacy. Every batch is tested for purity, sterility, potency, and identity. Certificates of Analysis are available on request.

  • HPLC purity testing
  • LC-MS identity confirmation
  • Sterility and endotoxin testing
  • Heavy metals screening
  • Purity: greater than or equal to 99%

For research and investigational use by qualified healthcare practitioners only. Not for human consumption. Not for resale. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Certificate of Analysis available on request. Questions? Call or text 507-382-2881.

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Disclaimer, Terms of Use, and Assumption of Risk

All products on this website are sold strictly for laboratory research and educational purposes only. They are not for human or animal consumption and are not intended to diagnose, treat, cure, or prevent any disease. None of the products or statements here have been evaluated or approved by the FDA, and nothing on this site constitutes medical advice or creates any provider and patient relationship.

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