Description
Form: Ready to use vial | Purity: ≥99% | Storage: Refrigerate
What It Is
Kisspeptin is a neuropeptide produced in the hypothalamus that acts as the master regulator of the reproductive hormone axis. It is the primary trigger for GnRH (gonadotropin-releasing hormone) release, which drives LH, FSH, testosterone, and estrogen production. It plays a central role in puberty, fertility, and reproductive health.
What It Does
Kisspeptin stimulates GnRH release, which increases LH and FSH, which in turn drive testosterone and estrogen production. It improves libido and sexual function in both men and women, supports fertility, and has been studied for hypogonadism, hypothalamic amenorrhea, and sexual dysfunction.
How It Works
Kisspeptin binds to KISS1R receptors on GnRH neurons in the hypothalamus, triggering a cascade that activates the entire reproductive hormone axis. This upstream activation is more physiologically complete than direct testosterone or estrogen supplementation because it works through the body’s own regulatory system.
Who Benefits Most
Men and women with low libido or sexual dysfunction. Women with hypothalamic amenorrhea or irregular cycles. Men with low testosterone who want to support natural production. Couples working on fertility. People with functional hypogonadism related to stress, overtraining, or caloric restriction.
Protocol and Dosing
Typical dose: 1 to 10 nmol/kg injected subcutaneously. Dosing is highly individualized. Often used in pulsatile protocols to mimic natural GnRH release patterns. Work with a practitioner to determine the right protocol for your specific situation.
| Application | Typical Dose | Notes |
|---|---|---|
| Sexual function | 1 to 10 nmol/kg | Highly individualized |
| Fertility support | Pulsatile protocol | Requires practitioner guidance |
Cautions
Dosing is complex and highly individualized. Use under practitioner supervision. Effects on the reproductive axis are significant. Not for use during pregnancy. Not recommended for people with hormone-sensitive cancers.
Pairs Well With
PT-141 for comprehensive sexual function support through complementary pathways. Testosterone optimization protocols for men. Hormone optimization protocols for women. Sermorelin or Ipamorelin for comprehensive endocrine optimization.
Quality and Sourcing
Sourced through United Medical Services (UMS), a compounding facility built to the same standards as a licensed 503A pharmacy. Every batch is tested for purity, sterility, potency, and identity. Certificates of Analysis are available on request.
- HPLC purity testing
- LC-MS identity confirmation
- Sterility and endotoxin testing
- Heavy metals screening
- Purity: greater than or equal to 99%
For research and investigational use by qualified healthcare practitioners only. Not for human consumption. Not for resale. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Certificate of Analysis available on request. Questions? Call or text 507-382-2881.
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